Research presentation
Fredrik Hellström
Associate professor, Head of department
Research subject: Occupational Health Sciences
Email: fredrik.hellstrom@hig.se
Telephone: +46 26 64 86 60
Mobile: +46 70 532 40 83
- Magisterexamen i molekylärbiologi
- Fil. Dr i Idrottsmedicin
CURRENT RESEARCH
- Biochemical characteristics
- Multivariate modelling
- Biomarkers in blood and microdialysis tests
- Stress, inflammation and blood flow during repetitive arm work with a focus on gender, age and work-related pain
- Rehabilitation of women with neck pain. Effects of individualized treatment based on prognostic indicators and tests of functioning
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Articles
Scholarly articles, refereed
Böthun, A., Häggman‐Henrikson, B., Stålnacke, B., Wänman, A., Nordh, E., Lampa, E. & Hellström, F. (2023). Clinical signs in the jaw and neck region following whiplash trauma – a 2‐year follow‐up. European Journal of Pain, 27 (6), 699-709. 10.1002/ejp.2099
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Nilsson, E., Häggman‐Henrikson, B., Domellöf, E., Hellström, F., Häger, C. & Österlund, C. (2023). Development of integrated jaw‐neck motor function in children at 6, 10 and 13 years of age compared to adults: a kinematic longitudinal study. Journal of Oral Rehabilitation, 50 (10), 1002-1011. 10.1111/joor.13539
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Böthun, A., Häggman‐Henrikson, B., Wiesinger, B., Wänman, A., Hellström, F. & Österlund, C. (2022). Jaw–neck motor strategy during jaw‐opening with resistance load. Journal of Oral Rehabilitation, 49 (5), 514-521. 10.1111/joor.13291
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Sjödin, A., Hellström, F., Sehlstedt, E., Svensson, M. & Burén, J. (2020). Effects of a ketogenic diet on muscle fatigue in healthy, young, normal-weight women : a randomized controlled feeding trial. Nutrients, 12 (4). 10.3390/nu12040955
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Österlund, C., Nilsson, E., Hellström, F., Häger, C. & Häggman-Henrikson, B. (2020). Jaw-neck movement integration in 6-year old children differs from that of adults. Journal of Oral Rehabilitation, 47 (1), 27-35. 10.1111/joor.12865
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Wiesinger, B., Häggman-Henrikson, B., Eklund, A., Wänman, A. & Hellström, F. (2019). Multimodal Sensory Stimulation of the Masseter Muscle Reduced Precision but Not Accuracy of Jaw-Opening Movements. Frontiers in Neuroscience, 13. 10.3389/fnins.2019.01083
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Lövgren, A., Österlund, C., Lampa, E., Ilgunas, A. & Hellström, F. (2018). A high prevalence of TMD is related to somatic awareness and pain intensity among healthy dental students. Acta Odontologica Scandinavica, 76 (6), 387-393. 10.1080/00016357.2018.1440322
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Gold, J., Hallman, D., Hellström, F., Björklund, M., Crenshaw, A., Mathiassen, S., Barbe, M. & Ali, S. (2017). Systematic review of quantitative imaging biomarkers for neck and shoulder musculoskeletal disorders. BMC Musculoskeletal Disorders, 18. 10.1186/s12891-017-1694-y
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Hellström, F., Gouveia-Figueira, S., Nording, M., Björklund, M. & Fowler, C. (2016). Association between plasma concentrations of linoleic acid-derived oxylipins and the perceived pain scores in an exploratory study in women with chronic neck pain. BMC Musculoskeletal Disorders, 17 (1). 10.1186/s12891-016-0951-9
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Wiesinger, B., Häggman-Henrikson, B., Hellström, F., Englund, E. & Wänman, A. (2016). Does induced masseter muscle pain affect integrated jaw-neck movements similarly in men and women?. European Journal of Oral Sciences, 124 (6), 546-553. 10.1111/eos.12315
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Hadrévi, J., Turkina, M., Carlsson, A., Gerdle, B., Larsson, B., Hellström, F. & Ghafouri, B. (2016). Myosin light chain and calcium regulating protein differences in chronic musculoskeletal neck and shoulder pain. Journal of Integrated OMICS, 6 (1), 1-8. 10.5584/jiomics.v6i1.191
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Gold, J., Hallman, D., Hellström, F., Björklund, M., Crenshaw, A., Djupsjöbacka, M., Heiden, M., Mathiassen, S., Piligian, G. & Barbe, M. (2016). Systematic review of biochemical biomarkers for neck and upper-extremity musculoskeletal disorders. Scandinavian Journal of Work, Environment and Health, 42 (2), 103-124. 10.5271/sjweh.3533
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Hadrévi, J., Björklund, M., Kosek, E., Hällgren, S., Antti, H., Fahlström, M. & Hellström, F. (2015). Systemic differences in serum metabolome : a cross sectional comparison of women with localised and widespread pain and controls. Scientific Reports, 5. 10.1038/srep15925
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Wiesinger, B., Häggman-Henriksson, B., Wänman, A., Lindqvist, M. & Hellström, F. (2014). Jaw-opening accuracy is not affected by masseter muscle vibration in healthy men. Experimental Brain Research, 232 (11), 3501-3508. 10.1007/s00221-014-4037-3
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Hadrevi, J., Ghafouri, B., Sjörs, A., Antti, H., Larsson, B., Crenshaw, A., Gerdle, B. & Hellström, F. (2013). Comparative metabolomics of muscle interstitium fluid in human trapezius myalgia : an <em></em>in vivo microdialysis study. European Journal of Applied Physiology, 113 (12), 2977-2989. 10.1007/s00421-013-2716-6
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Wiesinger, B., Häggman-Henrikson, B., Hellström, F. & Wänman, A. (2013). Experimental masseter muscle pain alters jaw-neck motor strategy. European Journal of Pain, 17 (7), 995-1004. 10.1002/j.1532-2149.2012.00263.x
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Hadrevi, J., Ghafouri, B., Larsson, B., Gerdle, B. & Hellström, F. (2013). Multivariate modeling of proteins related to trapezius myalgia, a comparative study of female cleaners with or without pain. PLOS ONE, 8 (9), e73285-. 10.1371/journal.pone.0073285
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Crenshaw, A., Elcadi, G., Hellström, F. & Mathiassen, S. (2012). Reliability of near infrared spectroscopy for measuring forearm and shoulder oxygenation in healthy males and females. European Journal of Applied Physiology, 112, 2703-2715. 10.1007/s00421-011-2244-1
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Hadrevi, J., Hellström, F., Kieselbach, T., Malm, C. & Pedrosa-Domellöf, F. (2011). Protein differences between human trapezius and vastus lateralis muscles determined with a proteomic approach. BMC Musculoskeletal Disorders, 12 (181). 10.1186/1471-2474-12-181
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Flodgren, G., Crenshaw, A., Hellström, F. & Fahlström, M. (2010). Combining microdialysis and near infrared spectroscopy for studying effects of low-load repetitive work on the intramuscular chemistry in trapezius myalgia. Journal of Biomedicine and Biotechnology, 2010. 10.1155/2010/513803
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Schomburg, E., Steffens, H., Maznychenko, A., Pilyavskii, A., Hellström, F., Kostyukov, A. & Maisky, V. (2007). Acute muscle inflammation enhances the monosynaptic reflexes and c-fos expression in the feline spinal cord. European Journal of Pain, 11 (5), 579-586. 10.1016/j.ejpain.2006.09.004
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Crenshaw, A., Lyskov, E., Heiden, M., Flodgren, G. & Hellström, F. (2007). Impact of time pressure and pauses on physiological responses to standardized computer mouse use : a review of three papers with focusing on mechanisms behind computer-related disorders. Scandinavian Journal of Work, Environment and Health (3), 68-75.
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Mel'nichouk, A., Bulgakova, N., Tal'nov, A., Hellström, F., Windhorst, U. & Kostyukov, A. (2007). Movement-dependent positioning errors in human elbow joint movements. Experimental Brain Research, 176 (2), 237-247. 10.1007/s00221-006-0612-6
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Flodgren, G., Hellström, F., Fahlström, M. & Crenshaw, A. (2006). Effects of 30 versus 60 min of low-load work on intramuscular lactate, pyruvate, glutamate, prostaglandin E(2) and oxygenation in the trapezius muscle of healthy females. European Journal of Applied Physiology, 97 (5), 557-565. 10.1007/s00421-006-0216-7
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Pilyavskii, A., Maznychenko, A., Maisky, V., Kostyukov, A., Hellström, F. & Windhorst, U. (2005). Capsaicin-induced effects on c-fos expression and NADPH-diaphorase activity in the feline spinal cord.. European Journal of Pharmacology, 521 (1-3), 70-78. 10.1016/j.ejphar.2005.08.006
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Heiden, M., Lyskov, E., Djupsjöbacka, M., Hellström, F. & Crenshaw, A. (2005). Effects of time pressure and precision demands during computer mouse work on muscle oxygenation and position sense.. European journal of applied physiology, 94 (1-2), 97-106. 10.1007/s00421-004-1295-y
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Flodgren, G., Crenshaw, A., Alfredson, H., Fahlström, M., Hellström, F., Bronemo, L. & Djupsjöbacka, M. (2005). Glutamate and prostaglandin E2 in the trapezius muscle of female subjects with chronic muscle pain and controls determined by microdialysis.. European Journal of Pain, 9 (5), 511-515. 10.1016/j.ejpain.2004.11.004
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Hellström, F., Roatta, S., Thunberg, J., Passatore, M. & Djupsjöbacka, M. (2005). Responses of muscle spindles in feline dorsal neck muscles to electrical stimulation of the cervical sympathetic nerve.. Experimental Brain Research, 165 (3), 328-42. 10.1007/s00221-005-2309-7
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Hellström, F., Roatta, S., Johansson, H. & Passatore, M. (1999). A technique for estimating activity in whole nerve trunks applied to the cervical sympathetic trunk, in the rabbit. Neuroscience Letters, 277 (2), 95-98. 10.1016/S0304-3940(99)00849-6
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Pedersen, J., Lönn, J., Hellström, F., Djupsjöbacka, M. & Johansson, H. (1998). The effects of localized muscle fatigue on the movement sense in the dominant human shoulder. Medicine & Science in Sports & Exercise.
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Book chapters
Hellström, F. (2012). Work with Highly Repetitive Movements. Occupational Physiology. Bosa Roca: Crc Press Inc. P. 117-139.
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Hellström, F. (2008). Arbete med högrepetitiva rörelser. Arbetslivsfysiologi. Lund: Studentlitteratur AB. P. 161-190.
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Passatore, M., Hellström, F. & Roatta, S. (2004). The role of the sympathetic nervous system in stress and pain. International Congress on Chronic Pain and Dysfunction after Whiplash and other Traumatic Neck Injuries. Centre for Musculoskeletal Research, Gävle, Sweden: Gefle University Press. P. 16-26.
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Conference papers
Rasmussen, C., Hallman, D. & Hellström, F. (2018). Symposia: Musculoskeletal pain as an outcome - how can we get better insight into the time course of musculoskeletal pain?. .
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Hallman, D., Mathiassen, S., Heiden, M., Birk Jørgensen, M., Holtermann, A., Rudolfsson, T., Björklund, M., Svedmark, Å., Djupsjöbacka, M., Hellström, F., Rönnlund Borg, T., Häger, C., Sommar, J. & Wahlström, J. (2018). Symposium: Arbete, individ och nacksmärta : Forskning vid Forte-centret “Kroppen i arbete – från problem till potential”. FALF KONFERENS 2018 Arbetet - problem eller potential för en hållbar livsmiljö? 10-12 juni 2018 i Gävle : Program och Abstracts. Gävle: Gävle University Press. P. 102-.
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Gold, J., Hallman, D., Hellström, F., Björklund, M., Mathiassen, S., Piligian, G. & Barbe, M. (2016). Biochemical biomarkers for MSDs : systematic review results. .
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Borg, T., Björklund, M., Djupsjöbacka, M., Wänman, A. & Hellström, F. (2016). Perceived muscular tension in healthy subjects : a cross-sectional study. PREMUS2016 : Book of abstracts. P. 411-411.
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Hellström, F., Djupsjöbacka, M. & Björklund, M. (2012). Metabolic profiles and inflammatory cytokines in people with generalized or local muscle pain. .
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Hadrevi, J., Ghafouri, B., Gerdle, B., Larsson, B., Pedrosa-Domellöf, F. & Hellström, F. (2010). Comprehensive analysis of the painful trapezius muscle using a proteomic method (Poster). Proceedings of the Premus 2010 conference (Seventh International Conference on Prevention of Work-Related Musculoskeletal Disorders) August 29-September 2.
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Flodgren, G., Crenshaw, A., Hellström, F. & Fahlström, M. (2008). Effects of low-load work on sensitizing substances and muscle metabolism in trapezius myalgia. .
External link
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Flodgren, G., Crenshaw, A., Hellström, F. & Fahlström, M. (2007). Effects of low-load repetitive work on sensitizing substances and metabolism in the trapezius muscle of female pain subjects and controls-determined with microdialysis and near infrared-spectroscopy. Sixth International Scientific Conference on Prevention of Work-Related Musculoskeletal Disorders. P. 275-.
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Hadrevi, J., Hellström, F., Malm, C., Frängsmyr, L. & Pedrosa-Domellöf, F. (2007). Evaluation of trapezius using proteomic methods. Sixth International Scientific Conference on Prevention of Work-Related Musculoskeletal Disorders. P. 274-.
External link
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Crenshaw, A., Lyskov, E., Heiden, M., Flodgren, G., Djupsjöbacka, M. & Hellström, F. (2007). Physiological responses to a standardized computer mouse task : implications for pathophysiological mechanisms behind computer related disorders. Work With Computing Systems - WWCS 2007, Stockholm : abstracts WWCS 2007 : Computing systems for human benefits from the 8th International Conference on Work With Computing Systems : May 21st-24th 2007, Stockholm Sweden. Stockholm: Royal Institute of Technology. P. 47-47.
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Hellström, F. (2007). Visualising receptors of pain producing substances in muscles using PET/CT in patients with musculoskeletal disorders. Sixth International Scientific Conference on Prevention of Work-Related Musculoskeletal Disorders. P. 278-.
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Hellström, F. & Djupsjöbacka, M. (2005). How to explain the pain : the Brussels model. 6th Physiatric Summer School. Fibromyalgia. Helsinki: Rehabilitation ORTON Invalid Foundation.
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Flodgren, G., Crenshaw, A., Alfredson, H., Fahlström, M., Hellström, F., Bronemo, L. & Johansson, H. (2004). Interstitial PGE2 and glutamate levels in the trapezius muscle of females - determined by microdialysis (poster). Medicine & Science in Sports & Exercise : May 2004 - Volume 36 - Issue 5 - p S332.
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Passatore, M., Hellström, F. & Roatta, S. (2004). The role of the sympathetic nervous system in stress and pain. Proceedings of international Congress on Chronic Pain and Dysfunction after Whiplash and other Traumatic Neck Injuries. Gävle: Gefe University Press. P. 16-26.
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Reports
Rudolfsson, T. & Hellström, F. (2021). Utvärdering av fyra arbetsmiljöåtgärder inom schemalagt och flexibelt arbete. Gävle: Högskolan i Gävle; Trafikverket. 46 p.
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